Volver a Ensayos Clínicos
NCT05174169
Quimioterapia adyuvante para el cáncer de colon basada en la evaluación de la enfermedad residual.
Reclutando
Fase 2
Descripción
Este ensayo de fase II/III evaluará qué tipo de quimioterapia se debe recomendar a los pacientes en función de la presencia o ausencia de ADN tumoral circulante (ctDNA) tras la cirugía para el cáncer de colon.
Evidencia de la diana molecular en cáncer colorrectal
Estos fármacos NO son el fármaco de este ensayo. Es la eficacia publicada de OTROS fármacos que atacan la misma diana molecular, mostrada como contexto — no se refiere a este ensayo concreto ni confirma elegibilidad. Revísalo siempre con tu oncólogo.
Aún no hay evidencia documentada en nuestra base para la diana o el fármaco de este ensayo. Esta sección crece a medida que se procesan nuevas publicaciones.
Criterios de Elegibilidad
Criterios de inclusión:
El paciente debe tener un índice de estado funcional ECOG de 0 o 1.
Los pacientes deben tener un adenocarcinoma de colon en estadio IIB, IIC o III confirmado histológica/patológicamente con resección R0 según los criterios de la 8ª edición de la AJCC.
No debe haber evidencia radiográfica de enfermedad metastásica manifiesta en los 45 días previos al inicio del estudio/inclusión (se acepta una TC con contraste intravenoso o una resonancia magnética, que debe incluir tórax, abdomen y pelvis).
La extensión distal del tumor debe ser mayor o igual a 12 cm desde el borde anal en la colonoscopia o por encima de la reflexión peritoneal, según lo documentado durante la cirugía o en la muestra de patología (es decir, excluyendo los adenocarcinomas rectales que requieren tratamiento con quimiorradiación).
El paciente debe haber sido sometido a una resección tumoral completa en bloque (resección curativa). Los pacientes que hayan sido sometidos a un procedimiento quirúrgico en dos etapas, primero para realizar una colostomía de descompresión y luego, en un procedimiento posterior, para realizar la resección quirúrgica definitiva, son elegibles.
La muestra tumoral resecada y una muestra de sangre de pacientes con cáncer de colon en estadio IIB, IIC o III deben ser analizadas en un laboratorio central para detectar ctDNA mediante el ensayo Signatera™ de Natera (después del inicio del estudio/inclusión y antes de la aleatorización). El paciente debe tener suficiente tejido para cumplir con los requisitos del protocolo. Esta muestra de sangre para el ensayo Signatera debe recogerse después de la cirugía (y se recomienda que se recoja al menos 14 días después de la cirugía).
El tumor debe estar documentado como estable en microsatélites o tener proteínas de reparación de errores de emparejamiento intactas mediante pruebas de laboratorio aprobadas por la CLIA. Los pacientes cuyos tumores sean MSI-H o dMMR están excluidos.
El investigador principal debe considerar que el paciente es candidato para todos los agentes potenciales que se utilizarán en este ensayo (5-FU, LV, oxaliplatino e irinotecán).
El intervalo entre la cirugía (día 7 postoperatorio) y el inicio del estudio/inclusión no debe ser superior a 60 días. NOTA: El inicio del estudio/inclusión puede ocurrir tan pronto como el día 7 postoperatorio, pero no puede ocurrir después de 60 días a partir de la fecha real de la cirugía del paciente.
Disponibilidad y suministro de tejido tumoral quirúrgico adecuado para el diagnóstico molecular y la confirmación del perfil.
Función hematológica adecuada dentro de los 28 días previos al inicio del estudio/inclusión, definida de la siguiente manera:
- El recuento absoluto de neutrófilos (RAN) debe ser mayor o igual a 1500/mm3;
- Participantes con neutropenia étnica benigna (NEB): RAN inferior a 1300 mm3, son elegibles.
- La NEB (también conocida como neutropenia constitucional) es una causa hereditaria de neutropenia leve o moderada que no se asocia con un mayor riesgo de infecciones u otras manifestaciones clínicas. La NEB se denomina neutropenia étnica debido a su mayor prevalencia en personas de ascendencia africana y otros grupos étnicos específicos.
- El recuento de plaquetas debe ser mayor o igual a 100.000/mm3; y
- La hemoglobina debe ser mayor o igual a 9 g/dL.
Función hepática adecuada dentro de los 28 días previos al inicio del estudio/inclusión, definida de la siguiente manera:
- la bilirrubina total debe ser menor o igual al LSN (límite superior normal) para el laboratorio y
- la fosfatasa alcalina debe ser menor de 2,5 veces el LSN para el laboratorio; y
- la AST y la ALT deben ser menores de 2,5 veces el LSN para el laboratorio.
Función renal adecuada dentro de los 28 días previos al inicio del estudio/inclusión, definida como creatinina sérica menor o igual a 1,5 veces el LSN para el laboratorio o aclaramiento de creatinina medido o calculado mayor o igual a 50 ml/min utilizando la fórmula de Cockcroft-Gault para pacientes con niveles de creatinina mayores de 1,5 veces el LSN para el laboratorio.
Para mujeres, aclaramiento de creatinina (ml/min) = (140 - edad) x peso (kg) x 0,85 / 72 x creatinina sérica (mg/dL). Para hombres, aclaramiento de creatinina (ml/min) = (140 - edad) x peso (kg) / 72 x creatinina sérica (mg/dL). NOTA: Se debe utilizar el peso corporal ajustado (PCA) para los pacientes que tengan un IMC mayor o igual a 28 (menor o igual al 30 % por encima del PB ideal).
Los pacientes infectados por el VIH que estén en tratamiento antirretroviral eficaz con carga viral indetectable en los últimos 6 meses son elegibles para este ensayo.
La prueba de embarazo (orina o suero según el estándar institucional) realizada dentro de los 14 días previos al inicio del estudio/inclusión debe ser negativa (solo para mujeres en edad fértil).
Los pacientes que reciban un anticoagulante derivado de la cumarina deben aceptar una monitorización semanal del INR si se les asigna al brazo 1 o al brazo 3 y reciben capecitabina.
Criterios de elegibilidad para los pacientes del brazo 2 del grupo A en la segunda aleatorización:
El paciente debe haber desarrollado un ensayo ctDNA +ve durante el seguimiento seriado.
Se debe confirmar la disposición del paciente a ser re-aleatorizado.
El paciente debe seguir teniendo un índice de estado funcional ECOG de 0 o 1.
No debe haber evidencia radiográfica de enfermedad metastásica manifiesta.
La prueba de embarazo (orina o suero según el estándar institucional) realizada dentro de los 14 días previos a la segunda aleatorización debe ser negativa (solo para mujeres en edad fértil).
Función hematológica adecuada dentro de los 28 días previos a la segunda aleatorización, definida de la siguiente manera:
- El recuento absoluto de neutrófilos (RAN) debe ser mayor o igual a 1500/mm3;
- Participantes con neutropenia étnica benigna (NEB): RAN inferior a 1300 mm3, son elegibles.
- La NEB (también conocida como neutropenia constitucional) es una causa hereditaria de neutropenia leve o moderada que no se asocia con un mayor riesgo de infecciones u otras manifestaciones clínicas. La NEB se denomina neutropenia étnica debido a su mayor prevalencia en personas de ascendencia africana y otros grupos étnicos específicos.
- El recuento de plaquetas debe ser mayor o igual a 100.000/mm3; y
- La hemoglobina debe ser mayor o igual a 9 g/dL.
Función hepática adecuada dentro de los 28 días previos a la segunda aleatorización, definida de la siguiente manera:
- la bilirrubina total debe ser menor o igual al LSN (límite superior normal) para el laboratorio y
- la fosfatasa alcalina debe ser menor de 2,5 veces el LSN para el laboratorio; y
- la AST y la ALT deben ser menores de 2,5 veces el LSN para el laboratorio.
Función renal adecuada dentro de los 28 días previos a la segunda aleatorización, definida como creatinina sérica menor o igual a 1,5 veces el LSN para el laboratorio o aclaramiento de creatinina medido o calculado mayor o igual a 50 ml/min utilizando la fórmula de Cockcroft-Gault para pacientes con niveles de creatinina mayores de 1,5 veces el LSN para el laboratorio.
Para mujeres, aclaramiento de creatinina (ml/min) = (140 - edad) x peso (kg) x 0,85 / 72 x creatinina sérica (mg/dL). Para hombres, aclaramiento de creatinina (ml/min) = (140 - edad) x peso (kg) / 72 x creatinina sérica (mg/dL).
Criterios de exclusión:
Histología de cáncer de colon distinta de adenocarcinoma (es decir, carcinoma neuroendocrino, sarcoma, linfoma, carcinoma de células escamosas, etc.).
Evidencia patológica, clínica o radiológica de enfermedad metastásica manifiesta. Esto incluye metástasis intraabdominales aisladas, distantes o no contiguas, incluso si se han resecado.
Perforación intestinal relacionada con el tumor.
Antecedentes de cáncer de colon invasivo previo, independientemente del intervalo libre de enfermedad.
Antecedentes de trasplante de médula ósea o de órganos sólidos (independientemente de las necesidades actuales de terapia inmunosupresora). Los injertos óseos, los injertos de piel, los trasplantes de córnea y la donación de órganos/tejidos no son criterios de exclusión.
Quimioterapia sistémica, terapia dirigida o inmunoterapia previa; o radioterapia administrada como tratamiento para el cáncer colorrectal (por ejemplo, los adenocarcinomas primarios de colon para los que se justifica el tratamiento con quimioterapia y/o radioterapia neoadyuvantes no están permitidos). EXCEPCIÓN: se permite, pero no es obligatorio, un ciclo de quimioterapia (régimen a discreción del médico tratante: 5-FU o capecitabina con o sin oxaliplatino) después del consentimiento. El ciclo opcional de quimioterapia debe iniciarse al menos 4 semanas después de la cirugía y mientras se espera la aleatorización en la etapa 2.
Otro cáncer invasivo en los 5 años previos al inicio del estudio/inclusión. Las excepciones son los pólipos colorrectales, el cáncer de piel no melanoma o cualquier carcinoma in situ.
Cánceres primarios rectales y/o de colon sincrónicos.
Pacientes con antecedentes conocidos o síntomas actuales de enfermedad cardíaca, o con antecedentes de tratamiento con agentes cardiotóxicos, deben someterse a una evaluación del riesgo clínico de la función cardíaca utilizando la clasificación funcional de la Asociación Cardíaca de Nueva York. Para ser elegibles para este ensayo, los pacientes deben estar en la clase 2B o superior.
Neuropatía sensorial o motora mayor o igual a grado 2, según CTCAE v5.0.
Transfusión de sangre en las dos semanas previas a la recolección de sangre para las pruebas de ctDNA centralizadas.
Trastorno convulsivo activo no controlado con medicación.
Infección activa o crónica que requiera terapia sistémica.
Deficiencia conocida de DPD (dihidropirimidina deshidrogenasa) homocigota.
Pacientes con síndrome de Gilbert conocido o homocigotosidad para el polimorfismo UGT1A1\*28.
Embarazo o lactancia en el momento del inicio del estudio/inclusión.
Enfermedades concomitantes u otras enfermedades que harían que el paciente no fuera adecuado para la inclusión en este estudio (es decir, incapaz de tolerar 6 meses de quimioterapia combinada o que interfieran significativamente con la evaluación adecuada de la seguridad y la toxicidad de los regímenes prescritos o que impidan el seguimiento necesario).
Criterios de inelegibilidad para los pacientes del brazo 2 del grupo A en la segunda aleatorización:
Embarazo o lactancia en el momento de la aleatorización.
Ya no es candidato para la quimioterapia sistémica (FOLFOX, CAPOX y mFOLFIRINOX), según el criterio del investigador principal.
Información del Ensayo
NCT05174169
Reclutando
Fase 2
1912 participantes
Jul 2022
Mar 2029
Ubicaciones1077
Canada (31)
Royal Victoria Regional Health Centre
Barrie
Arthur J E Child Comprehensive Cancer Centre
Calgary
Cambridge Memorial Hospital
Cambridge
CSSS Champlain-Charles Le Moyne
Greenfield Park
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton
Kingston Health Sciences Centre
Kingston
Waterloo Regional Health Network
Kitchener
Hotel-Dieu De Levis
Lévis
London Regional Cancer Program
London
Markham Stouffville Hospital
Markham
CIUSSSEMTL-Hopital Maisonneuve-Rosemont
Montreal
Hopital Du Sacre-Coeur de Montreal
Montreal
Jewish General Hospital
Montreal
Stronach Regional Health Centre at Southlake
Newmarket
Lakeridge Health Oshawa
Oshawa
Ottawa Hospital and Cancer Center-General Campus
Ottawa
BCCA-Cancer Centre for the North
Prince George
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
Québec
Allan Blair Cancer Centre
Regina
Niagara Health System-Saint Catharines General
Saint Catharines
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John
Saskatoon Cancer Centre
Saskatoon
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke
Doctor H. Bliss Murphy Cancer Centre
St. John's
Humber River Hospital
Toronto
North York General Hospital
Toronto
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto
Saint Michael's Hospital
Toronto
BCCA-Vancouver Cancer Centre
Vancouver
BCCA-Vancouver Island Cancer Centre
Victoria
Windsor Regional Cancer Centre
Windsor
Puerto Rico (9)
Pan American Center for Oncology Trials LLC - Cayey
Cayey
Pan American Center for Oncology Trials LLC - Dorado
Dorado
Doctors Cancer Center
Manati
Centro Comprensivo de Cancer de UPR
San Juan
Pan American Center for Oncology Trials LLC
San Juan
Pan American Center for Oncology Trials LLC - Ciudadela
San Juan
Pan American Center for Oncology Trials LLC - Mayaguez
San Juan
PROncology
San Juan
San Juan City Hospital
San Juan
United States (1037)
Hawaii Cancer Care - Westridge
‘Aiea
Pali Momi Medical Center
‘Aiea
The Queen's Medical Center - West Oahu
‘Ewa Beach
Abbeville General Hospital
Abbeville
Avera Cancer Institute-Aberdeen
Aberdeen
UM Upper Chesapeake Hematology and Oncology - Aberdeen
Aberdeen
Cleveland Clinic Akron General
Akron
Summa Health System - Akron Campus
Akron
Phoebe Putney Memorial Hospital
Albany
Presbyterian Kaseman Hospital
Albuquerque
University of New Mexico Cancer Center
Albuquerque
Lehigh Valley Hospital-Cedar Crest
Allentown
Aultman Alliance Community Hospital
Alliance
AdventHealth Altamonte
Altamonte Springs
OSF Saint Anthony's Health Center
Alton
UPMC Altoona
Altoona
The Don and Sybil Harrington Cancer Center
Amarillo
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork
Mary Greeley Medical Center
Ames
McFarland Clinic - Ames
Ames
Community Hospital of Anaconda
Anaconda
Kaiser Permanente-Anaheim
Anaheim
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor
University of Michigan Rogel Cancer Center
Ann Arbor
Aspirus Cancer Care-Antigo-Volm Cancer Center
Antigo
Kaiser Permanente-Deer Valley Medical Center
Antioch
Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton
Appleton
ThedaCare Regional Cancer Center
Appleton
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande
PCR Oncology
Arroyo Grande
Duluth Clinic Ashland
Ashland
University Cancer and Blood Center LLC
Athens
Northside Hospital
Atlanta
Piedmont Hospital
Atlanta
Sutter Auburn Faith Hospital
Auburn
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn
Harold Alfond Center for Cancer Care
Augusta
Advocate Outpatient Center - Aurora
Aurora
Rush-Copley Medical Center
Aurora
UCHealth University of Colorado Hospital
Aurora
Dell Seton Medical Center at The University of Texas
Austin
University of Texas at Austin
Austin
UH Seidman Cancer Center at UH Avon Health Center
Avon
AIS Cancer Center at San Joaquin Community Hospital
Bakersfield
Kaiser Permanente-Baldwin Park
Baldwin Park
Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin
Greater Baltimore Medical Center
Baltimore
Kaiser Permanente-Woodlawn Medical Center
Baltimore
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore
MedStar Good Samaritan Hospital
Baltimore
Saint Agnes Hospital
Baltimore
Sinai Hospital of Baltimore
Baltimore
Summa Health System - Barberton Campus
Barberton
CommonSpirit Saint Joseph Hospital - Bardstown
Bardstown
Advocate Good Shepherd Hospital
Barrington
LSU Health Baton Rouge-North Clinic
Baton Rouge
Medical Center of Baton Rouge
Baton Rouge
Ochsner High Grove
Baton Rouge
Our Lady of the Lake Physician Group
Baton Rouge
Bronson Battle Creek
Battle Creek
UHHS-Chagrin Highlands Medical Center
Beachwood
UPMC-Heritage Valley Health System Beaver
Beaver
Indu and Raj Soin Medical Center
Beavercreek
UM Upper Chesapeake Medical Center
Bel Air
FHCC Overlake
Bellevue
Kaiser Permanente-Bellflower
Bellflower
Strecker Cancer Center-Belpre
Belpre
Sanford Joe Lueken Cancer Center
Bemidji
Alta Bates Summit Medical Center-Herrick Campus
Berkeley
Summit Medical Group
Berkeley Heights
ThedaCare Cancer Care - Berlin
Berlin
Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners
Lehigh Valley Hospital - Muhlenberg
Bethlehem
University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf
Beverly Hospital
Beverly
Tower Cancer Research Foundation
Beverly Hills
MaineHealth Maine Medical Center - Biddeford
Biddeford
Billings Clinic Cancer Center
Billings
Saint Vincent Frontier Cancer Center
Billings
University of Alabama at Birmingham Cancer Center
Birmingham
Sanford Bismarck Medical Center
Bismarck
Illinois CancerCare-Bloomington
Bloomington
Saint Elizabeth Boardman Hospital
Boardman
Prisma Health Cancer Institute - Spartanburg
Boiling Springs
Saint Alphonsus Cancer Care Center-Boise
Boise
Saint Luke's Cancer Institute - Boise
Boise
Central Care Cancer Center - Bolivar
Bolivar
McFarland Clinic - Boone
Boone
Boston Medical Center
Boston
Tufts Medical Center
Boston
Bozeman Health Deaconess Hospital
Bozeman
Essentia Health Saint Joseph's Medical Center
Brainerd
Cox Cancer Center Branson
Branson
United Hospital Center
Bridgeport
Dana-Farber Cancer Institute at Boston Medical Center - Brighton
Brighton
Intermountain Health Platte Valley Hospital
Brighton
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton
Trinity Health Medical Center - Brighton
Brighton
Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield
Brookfield
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn
Saint Joseph Regional Cancer Center
Bryan
Highline Medical Center-Main Campus
Burien
Kaiser Permanente-Burke Medical Center
Burke
Mills-Peninsula Medical Center
Burlingame
Aurora Cancer Care-Southern Lakes VLCC
Burlington
Lahey Clinic
Burlington
University of Vermont and State Agricultural College
Burlington
University of Vermont Medical Center
Burlington
Fairview Ridges Hospital
Burnsville
Minnesota Oncology - Burnsville
Burnsville
UPMC Hillman Cancer Center at Butler Health System
Butler
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell
Cambridge Medical Center
Cambridge
Marshall Cancer Center
Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park
UPMC Camp Hill
Camp Hill
Aultman Health Foundation
Canton
Cleveland Clinic Mercy Hospital
Canton
Illinois CancerCare-Canton
Canton
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton
Trinity Health Medical Center - Canton
Canton
Mercy Cancer Center - Cape Girardeau
Cape Girardeau
Saint Francis Medical Center
Cape Girardeau
AtlantiCare Health Park-Cape May Court House
Cape May Court House
Memorial Hospital of Carbondale
Carbondale
Carlisle Regional Cancer Center
Carlisle
Mercy Cancer Center - Carmichael
Carmichael
Mercy San Juan Medical Center
Carmichael
Caro Cancer Center
Caro
Saint Anthony Regional Hospital
Carroll
Carson Tahoe Regional Medical Center
Carson City
SIH Cancer Institute
Carterville
Illinois CancerCare-Carthage
Carthage
Duke Cancer Center Cary
Cary
UNC Health Cancer Care Cary
Cary
Waverly Hematology Oncology
Cary
Eden Hospital Medical Center
Castro Valley
Sandra L Maxwell Cancer Center
Cedar City
Mercy Hospital
Cedar Rapids
Oncology Associates at Mercy Medical Center
Cedar Rapids
Physicians' Clinic of Iowa PC
Cedar Rapids
AdventHealth Celebration
Celebration
Dayton Physicians LLC-Miami Valley South
Centerville
Miami Valley Hospital South
Centerville
Centralia Oncology Clinic
Centralia
WellSpan Medical Oncology and Hematology
Chambersburg
UNC Lineberger Comprehensive Cancer Center
Chapel Hill
Geauga Hospital
Chardon
Bon Secours Saint Francis Hospital
Charleston
Charleston Oncology - Roper
Charleston
Charleston Oncology - Saint Francis
Charleston
Medical University of South Carolina
Charleston
Roper Hospital
Charleston
West Virginia University Charleston Division
Charleston
Atrium Health Pineville/LCI-Pineville
Charlotte
Atrium Health University City/LCI-University
Charlotte
Carolinas Medical Center/Levine Cancer Institute
Charlotte
Levine Cancer Institute-Ballantyne
Charlotte
Levine Cancer Institute-SouthPark
Charlotte
Minnesota Oncology Hematology PA-Chaska
Chaska
Chelsea Hospital
Chelsea
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea
Jefferson Cherry Hill Hospital
Cherry Hill
Cancer Specialists of Tidewater Limited
Chesapeake
Advocate Illinois Masonic Medical Center
Chicago
John H Stroger Jr Hospital of Cook County
Chicago
Mount Sinai Hospital Medical Center
Chicago
Northwestern University
Chicago
Rush MD Anderson Cancer Center
Chicago
Swedish Covenant Hospital
Chicago
University of Chicago Comprehensive Cancer Center
Chicago
University of Illinois
Chicago
Enloe Medical Center
Chico
Adena Regional Medical Center
Chillicothe
Ascension Calumet Hospital-Chilton
Chilton
Marshfield Clinic-Chippewa Center
Chippewa Falls
Bethesda North Hospital
Cincinnati
Good Samaritan Hospital - Cincinnati
Cincinnati
Oncology Hematology Care Inc-Kenwood
Cincinnati
TriHealth Cancer Institute-Anderson
Cincinnati
TriHealth Cancer Institute-Westside
Cincinnati
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters
Clackamas Radiation Oncology Center
Clackamas
Providence Cancer Institute Clackamas Clinic
Clackamas
Hematology Oncology Consultants-Clarkston
Clarkston
Newland Medical Associates-Clarkston
Clarkston
Morton Plant Hospital
Clearwater
Case Western Reserve University
Cleveland
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland
Cleveland Clinic Foundation
Cleveland
MetroHealth Medical Center
Cleveland
MedStar Southern Maryland Hospital Center
Clinton
Southeastern Medical Oncology Center-Clinton
Clinton
Mercy Cancer Center-West Lakes
Clive
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive
Kootenai Health - Coeur d'Alene
Coeur d'Alene
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville
Memorial Hospital North
Colorado Springs
Penrose-Saint Francis Healthcare
Colorado Springs
Rocky Mountain Cancer Centers-Penrose
Colorado Springs
Saint Francis Cancer Center
Colorado Springs
UCHealth Memorial Hospital Central
Colorado Springs
MU Health - University Hospital/Ellis Fischel Cancer Center
Columbia
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus
Columbus Oncology and Hematology Associates Inc
Columbus
Doctors Hospital
Columbus
Grant Medical Center
Columbus
Mount Carmel East Hospital
Columbus
Mount Carmel Health Center West
Columbus
Ohio State University Comprehensive Cancer Center
Columbus
Riverside Methodist Hospital
Columbus
The Mark H Zangmeister Center
Columbus
Atrium Health Cabarrus/LCI-Concord
Concord
New Hampshire Oncology Hematology PA-Concord
Concord
UT MD Anderson - The Woodlands
Conroe
Mercy Hospital
Coon Rapids
Minnesota Oncology - Coon Rapids
Coon Rapids
Commonwealth Cancer Center-Corbin
Corbin
Alegent Health Mercy Hospital
Council Bluffs
Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington
UPMC Hillman Cancer Center - Passavant - Cranberry
Cranberry Township
Greater Regional Medical Center
Creston
Siteman Cancer Center at West County Hospital
Creve Coeur
Northwest Cancer Center - Crown Point
Crown Point
AMG Crystal Lake - Oncology
Crystal Lake
Aurora Saint Luke's South Shore
Cudahy
UPMC Western Maryland
Cumberland
Parkland Memorial Hospital
Dallas
UT Southwestern Simmons Cancer Center - RedBird
Dallas
UT Southwestern/Simmons Cancer Center-Dallas
Dallas
Danbury Hospital
Danbury
Carle at The Riverfront
Danville
Geisinger Medical Center
Danville
Sutter Davis Hospital
Davis
Dayton Physician LLC - Englewood
Dayton
Miami Valley Hospital
Dayton
Miami Valley Hospital North
Dayton
Premier Blood and Cancer Center
Dayton
Corewell Health Dearborn Hospital
Dearborn
Cancer Care Specialists of Illinois - Decatur
Decatur
Decatur Memorial Hospital
Decatur
Essentia Health - Deer River Clinic
Deer River
Northwestern Medicine Cancer Center Kishwaukee
DeKalb
Delaware Health Center-Grady Cancer Center
Delaware
Grady Memorial Hospital
Delaware
AdventHealth Porter
Denver
Denver Health Medical Center
Denver
Kaiser Permanente-Franklin
Denver
Saint Joseph Hospital - Cancer Centers of Colorado
Denver
UCHealth - Cherry Creek
Denver
Smilow Cancer Hospital-Derby Care Center
Derby
Iowa Methodist Medical Center
Des Moines
Mercy Medical Center - Des Moines
Des Moines
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines
Henry Ford Health Saint John Hospital
Detroit
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes
Dillon Health Center/Shaw Cancer Center
Dillon
Illinois CancerCare-Dixon
Dixon
Bayhealth Hospital Kent Campus
Dover
Advocate Good Samaritan Hospital
Downers Grove
City of Hope Comprehensive Cancer Center
Duarte
Columbus Oncology and Hematology Associates
Dublin
Dublin Methodist Hospital
Dublin
Epic Care-Dublin
Dublin
Kaiser Permanente Dublin
Dublin
Essentia Health Cancer Center
Duluth
Northside Hospital - Duluth
Duluth
CommonSpirit Cancer Center Mercy
Durango
Mercy Medical Center
Durango
Duke University Medical Center
Durham
Northwest Oncology LLC
Dyer
Prisma Health Cancer Institute - Easley
Easley
Henry Ford River District Hospital
East China Township
Pocono Medical Center
East Stroudsburg
HSHS Sacred Heart Hospital
Eau Claire
Marshfield Medical Center-EC Cancer Center
Eau Claire
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire
Fairview Southdale Hospital
Edina
Minnesota Oncology - Edina
Edina
STCC at DHR Health Institute for Research and Development
Edinburg
Swedish Cancer Institute-Edmonds
Edmonds
Shaw Cancer Center
Edwards
Carle Physician Group-Effingham
Effingham
Crossroads Cancer Center
Effingham
AtlantiCare Surgery Center
Egg Harbor
Advocate Sherman Hospital
Elgin
Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
Elizabeth
Mercy Cancer Center - Elk Grove
Elk Grove
Elmhurst Memorial Hospital
Elmhurst
Epic Care Partners in Cancer Care
Emeryville
Saint Elizabeth Hospital
Enumclaw
Ephrata Cancer Center
Ephrata
Saint Vincent Hospital
Erie
UPMC Hillman Cancer Center Erie
Erie
OSF Saint Francis Hospital and Medical Group
Escanaba
Illinois CancerCare-Eureka
Eureka
NorthShore University HealthSystem-Evanston Hospital
Evanston
Exeter Hospital
Exeter
Smilow Cancer Hospital Care Center-Fairfield
Fairfield
Thomas Hospital
Fairhope
Essentia Health Cancer Center-South University Clinic
Fargo
Sanford Broadway Medical Center
Fargo
Sanford Roger Maris Cancer Center
Fargo
Farmington Health Center
Farmington
Parkland Health Center - Farmington
Farmington
UPMC Cancer Center at UPMC Horizon
Farrell
Piedmont Fayette Hospital
Fayetteville
Saint Francis Hospital
Federal Way
Armes Family Cancer Center
Findlay
Blanchard Valley Hospital
Findlay
Orion Cancer Care
Findlay
Cancer Hematology Centers - Flint
Flint
Genesee Hematology Oncology PC
Flint
Genesys Hurley Cancer Institute
Flint
Hurley Medical Center
Flint
Summit Health - Florham Park Campus
Florham Park
The New York Hospital Medical Center of Queens
Flushing
Kaiser Permanente-Fontana
Fontana
Cancer Care and Hematology-Fort Collins
Fort Collins
Poudre Valley Hospital
Fort Collins
McFarland Clinic - Trinity Cancer Center
Fort Dodge
Eisenhower Army Medical Center
Fort Eisenhower
Holy Cross Hospital
Fort Lauderdale
Mercy Hospital Fort Smith
Fort Smith
Parkview Regional Medical Center
Fort Wayne
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth
Orange Coast Memorial Medical Center
Fountain Valley
Dana-Farber Cancer Institute at Foxborough
Foxborough
Atrium Medical Center-Middletown Regional Hospital
Franklin
Dayton Physicians LLC-Atrium
Franklin
Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson
Franklin
FMH James M Stockman Cancer Institute
Frederick
Frederick Memorial Hospital
Frederick
Kaiser Permanente-Fremont
Fremont
Palo Alto Medical Foundation-Fremont
Fremont
Washington Health
Fremont
Kaiser Permanente Fresno Orchard Plaza
Fresno
Kaiser Permanente-Fresno
Fresno
Unity Hospital
Fridley
Saint Luke's Cancer Institute - Fruitland
Fruitland
Gibbs Cancer Center-Gaffney
Gaffney
Central Ohio Breast and Endocrine Surgery
Gahanna
UF Health Cancer Institute - Gainesville
Gainesville
Kaiser Permanente-Gaithersburg Medical Center
Gaithersburg
Illinois CancerCare-Galesburg
Galesburg
Western Illinois Cancer Treatment Center
Galesburg
University of Texas Medical Branch
Galveston
Central Care Cancer Center - Garden City
Garden City
UNC Health Cancer Care Garner
Garner
CaroMont Regional Medical Center
Gastonia
Northwestern Medicine Cancer Center Delnor
Geneva
Aurora Health Care Germantown Health Center
Germantown
The West Clinic - Wolf River
Germantown
Adams Cancer Center
Gettysburg
Smilow Cancer Hospital Care Center at Glastonbury
Glastonbury
UM Baltimore Washington Medical Center/Tate Cancer Center
Glen Burnie
Glens Falls Hospital
Glens Falls
NorthShore University HealthSystem-Glenbrook Hospital
Glenview
Northwestern Medicine Glenview Outpatient Center
Glenview
Addison Gilbert Hospital
Gloucester
Peninsula Cancer Institute-Gloucester
Gloucester
Lutheran Hospital - Cancer Centers of Colorado
Golden
National Jewish Health-Western Hematology Oncology
Golden
Southeastern Medical Oncology Center-Goldsboro
Goldsboro
Aurora Cancer Care-Grafton
Grafton
Altru Cancer Center
Grand Forks
Nebraska Cancer Specialists/Oncology Hematology West PC
Grand Island
Grand Valley Oncology
Grand Junction
Saint Mary's Hospital and Regional Medical Center
Grand Junction
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids
Trinity Health Grand Rapids Hospital
Grand Rapids
Northwestern Medicine Grayslake Outpatient Center
Grayslake
Central Care Cancer Center - Great Bend
Great Bend
Benefis Sletten Cancer Institute
Great Falls
Great Falls Clinic
Great Falls
UCHealth Greeley Hospital
Greeley
Aurora BayCare Medical Center
Green Bay
Bellin Memorial Hospital
Green Bay
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay
Saint Vincent Hospital Cancer Center Green Bay
Green Bay
Northwell Health Cancer Institute at Huntington
Greenlawn
Cone Health Cancer Center
Greensboro
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg
Dayton Physicians LLC-Wayne
Greenville
East Carolina University
Greenville
Miami Valley Cancer Care and Infusion
Greenville
Prisma Health Cancer Institute - Butternut
Greenville
Prisma Health Cancer Institute - Eastside
Greenville
Prisma Health Cancer Institute - Faris
Greenville
Wayne Hospital
Greenville
Smilow Cancer Hospital Care Center at Greenwich
Greenwich
Gibbs Cancer Center-Pelham
Greer
Prisma Health Cancer Institute - Greer
Greer
Baptist Cancer Center-Grenada
Grenada
Legacy Mount Hood Medical Center
Gresham
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods
Mount Carmel Grove City Hospital
Grove City
Smilow Cancer Hospital Care Center - Guilford
Guilford
The Cancer Institute of New Jersey Hamilton
Hamilton
Kaiser Permanente South Bay
Harbor City
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg
Smilow Cancer Hospital Care Center at Saint Francis
Hartford
Ingalls Memorial Hospital
Harvey
Advocate South Suburban Hospital
Hazel Crest
Geisinger Medical Center-Cancer Center Hazleton
Hazleton
Lehigh Valley Hospital-Hazleton
Hazleton
Comprehensive Cancer Centers of Nevada - Henderson
Henderson
Margaret R Pardee Memorial Hospital
Hendersonville
Penn State Milton S Hershey Medical Center
Hershey
Essentia Health Hibbing Clinic
Hibbing
NorthShore University HealthSystem-Highland Park Hospital
Highland Park
UCHealth Highlands Ranch Hospital
Highlands Ranch
Edward Hines Jr VA Hospital
Hines
UChicago Medicine AdventHealth Cancer Institute Hinsdale
Hinsdale
Northwest Cancer Center - Hobart
Hobart
Saint Mary Medical Center
Hobart
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu
Kaiser Permanente Moanalua Medical Center
Honolulu
Queen's Cancer Cenrer - POB I
Honolulu
Queen's Cancer Center - Kuakini
Honolulu
Queen's Medical Center
Honolulu
Straub Clinic and Hospital
Honolulu
University of Hawaii Cancer Center
Honolulu
Providence Hood River Memorial Hospital
Hood River
CHI Saint Vincent Cancer Center Hot Springs
Hot Springs
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston
Ben Taub General Hospital
Houston
Lyndon Baines Johnson General Hospital
Houston
UT MD Anderson - West Houston
Houston
UT MD Anderson Cancer Center
Houston
Cleveland Clinic Cancer Center Independence
Independence
IRMC Cancer Center
Indiana
Saint Catherine Hospital
Indianapolis
University of Iowa/Holden Comprehensive Cancer Center
Iowa City
Dickinson County Healthcare System
Iron Mountain
City of Hope at Irvine Lennar
Irvine
Kaiser Permanente-Irvine
Irvine
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine
Swedish Cancer Institute-Issaquah
Issaquah
University of Mississippi Medical Center
Jackson
Baptist MD Anderson Cancer Center
Jacksonville
Southeastern Medical Oncology Center-Jacksonville
Jacksonville
Mercyhealth Hospital and Cancer Center - Janesville
Janesville
McFarland Clinic - Jefferson
Jefferson
MU Health Care Goldschmidt Cancer Center
Jefferson City
Jefferson Hospital
Jefferson Hills
Jersey City Medical Center
Jersey City
University of Wisconsin Carbone Cancer Center - Johnson Creek
Johnson Creek
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro
Freeman Health System
Joplin
Mercy Hospital Joplin
Joplin
Jupiter Medical Center
Jupiter
Beacon Kalamazoo Cancer Center
Kalamazoo
Bronson Methodist Hospital
Kalamazoo
West Michigan Cancer Center
Kalamazoo
Logan Health Medical Center
Kalispell
Saint Luke's Hospital of Kansas City
Kansas City
CHI Health Good Samaritan
Kearney
Kadlec Clinic Hematology and Oncology
Kennewick
Aurora Cancer Care-Kenosha South
Kenosha
Greater Dayton Cancer Center
Kettering
Kettering Medical Center
Kettering
Illinois CancerCare-Kewanee Clinic
Kewanee
Kingman Regional Medical Center
Kingman
FHCC at EvergreenHealth
Kirkland
AdventHealth Kissimmee
Kissimmee
Covenant Health Cancer Centers
Knoxville
Covenant Health Cancer Centers - West
Knoxville
University of Tennessee - Knoxville
Knoxville
Gundersen Lutheran Medical Center
La Crosse
Mayo Clinic Health System-Franciscan Healthcare
La Crosse
UC San Diego Moores Cancer Center
La Jolla
Marshfield Medical Center - Ladysmith
Ladysmith
Kaiser Permanente-Rock Creek
Lafayette
Saddleback Memorial Medical Center
Laguna Hills
UCI Health Laguna Hills
Laguna Hills
Northwestern Medicine Lake Forest Hospital
Lake Forest
Orlando Health Cancer Institute - Lake Mary
Lake Mary
Northwell Health/Center for Advanced Medicine
Lake Success
The Watson Clinic
Lakeland
CommonSpirit Saint Anthony Hospital Cancer Center
Lakewood
Monmouth Medical Center Southern Campus
Lakewood
Saint Clare Hospital
Lakewood
City of Hope Antelope Valley
Lancaster
Fairfield Medical Center
Lancaster
Lancaster General Ann B Barshinger Cancer Institute
Lancaster
Lancaster General Hospital
Lancaster
University of Michigan Health - Sparrow Lansing
Lansing
Kaiser Permanente - Largo Medical Center
Largo
Memorial Medical Center-Las Cruces
Las Cruces
Comprehensive Cancer Centers of Nevada
Las Vegas
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas
OptumCare Cancer Care at Charleston
Las Vegas
OptumCare Cancer Care at Fort Apache
Las Vegas
Northside Hospital - Gwinnett
Lawrenceville
Cancer Centers of Southwest Oklahoma Research
Lawton
UT MD Anderson - League City
League City
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon
Sechler Family Cancer Center
Lebanon
Saint Luke's East - Lee's Summit
Lee's Summit
Geisinger Medical Oncology-Lewisburg
Lewisburg
Baptist Health Hamburg
Lexington
Baptist Health Lexington
Lexington
CommonSpirit Saint Joseph Medical Center - East Lexington
Lexington
Saint Joseph Radiation Oncology Resource Center
Lexington
AMG Libertyville - Oncology
Libertyville
Condell Memorial Hospital
Libertyville
Saint Rita's Medical Center
Lima
Cancer Partners of Nebraska
Lincoln
Saint Elizabeth Regional Medical Center
Lincoln
Rush MD Anderson Cancer Center at Rush Lisle
Lisle
University of Arkansas for Medical Sciences
Little Rock
AdventHealth Littleton
Littleton
Cooperman Barnabas Medical Center
Livingston
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia
Logan Regional Hospital
Logan
Loma Linda University Medical Center
Loma Linda
Veterans Affairs Loma Linda Healthcare System
Loma Linda
CommonSpirit Saint Joseph Hospital London
London
The Dana-Farber Cancer Institute at Londonderry
Londonderry
Kaiser Permanente-Lone Tree
Lone Tree
UCHealth Lone Tree Health Center
Lone Tree
Long Beach Memorial Medical Center-Todd Cancer Institute
Long Beach
Monmouth Medical Center
Long Branch
Longmont United Hospital
Longmont
Rocky Mountain Cancer Centers-Longmont
Longmont
Cedars-Sinai Medical Center
Los Angeles
Kaiser Permanente Los Angeles Medical Center
Los Angeles
Kaiser Permanente West Los Angeles
Los Angeles
Keck Medicine of USC Koreatown
Los Angeles
Los Angeles General Medical Center
Los Angeles
USC / Norris Comprehensive Cancer Center
Los Angeles
Jewish Hospital
Louisville
Norton Audubon Hospital and Medical Campus
Louisville
Norton Brownsboro Hospital and Medical Campus
Louisville
Norton Hospital Pavilion and Medical Campus
Louisville
Saints Mary and Elizabeth Hospital
Louisville
The James Graham Brown Cancer Center at University of Louisville
Louisville
UofL Health Medical Center Northeast
Louisville
Medical Center of the Rockies
Loveland
Kaiser Permanente Lutherville - Timonium Medical Center
Lutherville
Centra Alan B Pearson Regional Cancer Center
Lynchburg
Henry Ford Saint John Hospital - Macomb Medical
Macomb
Henry Ford Warren Hospital - Breast Macomb
Macomb
Illinois CancerCare-Macomb
Macomb
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison
University of Wisconsin Carbone Cancer Center - University Hospital
Madison
Solinsky Center for Cancer Care
Manchester
Cleveland Clinic Cancer Center Mansfield
Mansfield
OhioHealth Mansfield Hospital
Mansfield
Fairview Clinics and Surgery Center Maple Grove
Maple Grove
Minnesota Oncology - Maple Grove
Maple Grove
Minnesota Oncology Hematology PA-Maplewood
Maplewood
Saint John's Hospital - Healtheast
Maplewood
Marietta Memorial Hospital
Marietta
Aurora Bay Area Medical Group-Marinette
Marinette
OhioHealth Marion General Hospital
Marion
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette
West Jefferson Medical Center
Marrero
McFarland Clinic - Marshalltown
Marshalltown
Marshfield Medical Center-Marshfield
Marshfield
Contra Costa Regional Medical Center
Martinez
WVUH-Berkely Medical Center
Martinsburg
Fremont - Rideout Cancer Center
Marysville
Carle Physician Group-Mattoon/Charleston
Mattoon
Hillcrest Hospital Cancer Center
Mayfield Heights
Loyola University Medical Center
Maywood
UPMC Cancer Center at UPMC McKeesport
McKeesport
Kaiser Permanente Tysons Corner Medical Center
McLean
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg
Bon Secours Memorial Regional Medical Center
Mechanicsville
Aspirus Medford Hospital
Medford
Summa Health Medina Medical Center
Medina
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis
Froedtert Menomonee Falls Hospital
Menomonee Falls
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor
Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon
Mequon
Saint Luke's Cancer Institute - Meridian
Meridian
Dana Farber-Merrimack Valley
Methuen
UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights
Garnet Health Medical Center
Middletown
Bon Secours Saint Francis Medical Center
Midlothian
Bayhealth Hospital Sussex Campus
Milford
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
Milford
Ascension Columbia Saint Mary's Hospital-Milwaukee Campus
Milwaukee
Aurora Cancer Care-Milwaukee
Milwaukee
Aurora Saint Luke's Medical Center
Milwaukee
Aurora Sinai Medical Center
Milwaukee
Medical College of Wisconsin
Milwaukee
NYU Langone Hospital - Long Island
Mineola
Abbott-Northwestern Hospital
Minneapolis
Health Partners Inc
Minneapolis
Hennepin County Medical Center
Minneapolis
Marshfield Medical Center - Minocqua
Minocqua
Community Medical Center
Missoula
Avera Cancer Institute - Mitchell
Mitchell
Mobile Infirmary Medical Center
Mobile
University of South Alabama Mitchell Cancer Institute
Mobile
Kaiser Permanente- Modesto MOB II
Modesto
Kaiser Permanente-Modesto
Modesto
Memorial Medical Center
Modesto
Trinity Medical Center
Moline
Atrium Health Union/LCI-Union
Monroe
Forbes Hospital
Monroeville
UPMC Hillman Cancer Center - Monroeville
Monroeville
Monticello Cancer Center
Monticello
UPMC Hillman Cancer Center in Coraopolis
Moon Township
Essentia Health - Moose Lake Clinic
Moose Lake
West Virginia University Healthcare
Morgantown
Morristown Medical Center
Morristown
Northern Westchester Hospital
Mount Kisco
Knox Community Hospital
Mount Vernon
SSM Health Good Samaritan
Mount Vernon
Palo Alto Medical Foundation-Camino Division
Mountain View
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View
ProHealth D N Greenwald Center
Mukwonago
The Community Hospital
Munster
Women's Diagnostic Center - Munster
Munster
Intermountain Medical Center
Murray
Trinity Health Muskegon Hospital
Muskegon
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon
Saint Alphonsus Cancer Care Center-Nampa
Nampa
Saint Luke's Cancer Institute - Nampa
Nampa
Edward Hospital/Cancer Center
Naperville
Vanderbilt University/Ingram Cancer Center
Nashville
Allegheny Valley Hospital
Natrona Heights
UPMC Cancer Center-Natrona Heights
Natrona Heights
ThedaCare Regional Medical Center - Neenah
Neenah
Marshfield Medical Center - Neillsville
Neillsville
Baptist Memorial Hospital and Cancer Center-Union County
New Albany
Mount Carmel New Albany Surgical Hospital
New Albany
Rutgers Cancer Institute of New Jersey
New Brunswick
UPMC Hillman Cancer Center - New Castle
New Castle
Smilow Cancer Center/Yale-New Haven Hospital
New Haven
Yale University
New Haven
UC Comprehensive Cancer Center at Silver Cross
New Lenox
Louisiana State University Health Science Center
New Orleans
Ochsner Medical Center Jefferson
New Orleans
University Medical Center New Orleans
New Orleans
Cancer Center of Western Wisconsin
New Richmond
New Ulm Medical Center
New Ulm
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York
Lenox Hill Hospital
New York
Manhattan Eye Ear and Throat Hospital
New York
Mount Sinai Hospital
New York
Mount Sinai West
New York
NYP/Weill Cornell Medical Center
New York
Helen F Graham Cancer Center
Newark
Licking Memorial Hospital
Newark
Medical Oncology Hematology Consultants PA
Newark
Newark Beth Israel Medical Center
Newark
Newark Radiation Oncology
Newark
Rutgers New Jersey Medical School
Newark
Providence Newberg Medical Center
Newberg
CTCA at Southeastern Regional Medical Center
Newnan
Piedmont Newnan Hospital
Newnan
USC Norris Oncology/Hematology-Newport Beach
Newport Beach
Peninsula Cancer Institute-Newport News
Newport News
Yale-New Haven Hospital North Haven Medical Center
North Haven
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores
Norwalk Hospital
Norwalk
Sutter Cancer Research Consortium
Novato
Henry Ford Health Providence Novi Hospital
Novi
Cancer Care Center of O'Fallon
O'Fallon
Drexel Town Square Health Center
Oak Creek
Advocate Christ Medical Center
Oak Lawn
Rush MD Anderson Cancer Center at Rush Oak Park
Oak Park
Covenant Health Oncology Group - Oak Ridge
Oak Ridge
Bay Area Tumor Institute
Oakland
Kaiser Permanente-Oakland
Oakland
Mount Sinai South Nassau
Oceanside
ProHealth Oconomowoc Memorial Hospital
Oconomowoc
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls
McKay-Dee Hospital Center
Ogden
Integris Cancer Institute of Oklahoma
Oklahoma City
Integris Southwest Medical Center
Oklahoma City
Mercy Hospital Oklahoma City
Oklahoma City
University of Oklahoma Health Sciences Center
Oklahoma City
MedStar Montgomery Medical Center
Olney
Alegent Health Bergan Mercy Medical Center
Omaha
Alegent Health Immanuel Medical Center
Omaha
Alegent Health Lakeside Hospital
Omaha
Kaiser Permanente-Ontario
Ontario
Saint Alphonsus Cancer Care Center-Ontario
Ontario
Saint Joseph Hospital - Orange
Orange
Smilow Cancer Hospital-Orange Care Center
Orange
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange
Providence Willamette Falls Medical Center
Oregon City
Northwestern Medicine Orland Park
Orland Park
University of Chicago Medicine-Orland Park
Orland Park
AdventHealth East Orlando
Orlando
AdventHealth Orlando
Orlando
Orlando Health Cancer Institute
Orlando
Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh
Oshkosh
ThedaCare Cancer Care - Oshkosh
Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh
Illinois CancerCare-Ottawa Clinic
Ottawa
Saint Luke's South Hospital
Overland Park
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford
Palo Alto Medical Foundation Health Care
Palo Alto
VA Palo Alto Health Care System
Palo Alto
Kaiser Permanente - Panorama City
Panorama City
Midlands Community Hospital
Papillion
The Valley Hospital - Luckow Pavilion
Paramus
Advocate Lutheran General Hospital
Park Ridge
AdventHealth Parker
Parker
Camden Clark Medical Center
Parkersburg
University Hospitals Parma Medical Center
Parma
Lahey Clinic Peabody
Peabody
Illinois CancerCare-Pekin
Pekin
Memorial Hospital West
Pembroke Pines
Illinois CancerCare-Peoria
Peoria
Methodist Medical Center of Illinois
Peoria
Mercy Health - Perrysburg Hospital
Perrysburg
Illinois CancerCare-Peru
Peru
Valley Radiation Oncology
Peru
Fox Chase Cancer Center
Philadelphia
Jefferson Methodist Hospital
Philadelphia
Jefferson Torresdale Hospital
Philadelphia
Pennsylvania Hospital
Philadelphia
Thomas Jefferson University Hospital
Philadelphia
University of Pennsylvania/Abramson Cancer Center
Philadelphia
Cancer Center at Saint Joseph's
Phoenix
Mayo Clinic Hospital in Arizona
Phoenix
Reading Hospital McGlinn Cancer Institute at Phoenixville
Phoenixville
Avera Cancer Institute at Pierre
Pierre
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst
Allegheny General Hospital
Pittsburgh
UPMC Hillman Cancer Center
Pittsburgh
UPMC-Mercy Hospital
Pittsburgh
UPMC-Passavant Hospital
Pittsburgh
UPMC-Presbyterian Hospital
Pittsburgh
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh
UPMC-Saint Margaret
Pittsburgh
UPMC-Shadyside Hospital
Pittsburgh
West Penn Hospital
Pittsburgh
Edward Hospital/Cancer Center?Plainfield
Plainfield
South Florida Baptist Hospital
Plant City
Hope Cancer Center
Pontiac
Michigan Healthcare Professionals Pontiac
Pontiac
Newland Medical Associates-Pontiac
Pontiac
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac
Kaiser Permanente Northwest
Portland
Legacy Good Samaritan Hospital and Medical Center
Portland
Providence Portland Medical Center
Portland
Providence Saint Vincent Medical Center
Portland
Southern Ohio Medical Center
Portsmouth
Kootenai Clinic Cancer Services - Post Falls
Post Falls
Vassar Brothers Medical Center
Poughkeepsie
Fairview Northland Medical Center
Princeton
Illinois CancerCare-Princeton
Princeton
Roger Williams Medical Center
Providence
Utah Valley Regional Medical Center
Provo
Saint Mary Corwin Medical Center
Pueblo
Ascension All Saints Hospital-Spring Street-Racine
Racine
Aurora Cancer Care-Racine
Racine
Duke Cancer Center Raleigh
Raleigh
UNC Health Cancer Care Raleigh
Raleigh
UNC Health Cancer Care Wakefield
Raleigh
Eisenhower Medical Center
Rancho Mirage
Rapid City Regional Hospital
Rapid City
University Hospitals Portage Medical Center
Ravenna
Kaiser Permanente- Marshall Medical Offices
Redwood City
Corewell Health Reed City Hospital
Reed City
Queens Cancer Center
Rego Park
Renown Regional Medical Center
Reno
Saint Mary's Regional Medical Center
Reno
Valley Medical Center
Renton
Aspirus Cancer Care-Rhinelander-James Beck Cancer Center
Rhinelander
Marshfield Medical Center-Rice Lake
Rice Lake
UT Southwestern Clinical Center at Richardson/Plano
Richardson
Bon Secours Richmond Community Hospital
Richmond
Bon Secours Saint Mary's Hospital
Richmond
Kaiser Permanente-Richmond
Richmond
Reid Health
Richmond
VCU Massey Cancer Center at Stony Point
Richmond
VCU Massey Comprehensive Cancer Center
Richmond
Virginia Cancer Institute
Richmond
Valley Health System Ridgewood Campus
Ridgewood
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho
Kaiser Permanente-Riverside
Riverside
Riverton Hospital
Riverton
North Memorial Medical Health Center
Robbinsdale
Mayo Clinic in Rochester
Rochester
Rochester General Hospital
Rochester
Unity Park Ridge Campus
Rochester
University of Rochester
Rochester
UW Health Carbone Cancer Center Rockford
Rockford
Mercy Cancer Center - Rocklin
Rocklin
Mount Sinai - Rockville Center
Rockville Centre
Mercy Clinic-Rolla-Cancer and Hematology
Rolla
Phelps Health Delbert Day Cancer Institute
Rolla
Kaiser Permanente-Roseville
Roseville
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville
Sutter Roseville Medical Center
Roseville
Corewell Health William Beaumont University Hospital
Royal Oak
Kaiser Permanente Downtown Commons
Sacramento
Kaiser Permanente-South Sacramento
Sacramento
Mercy Cancer Center - Sacramento
Sacramento
Sutter Medical Center Sacramento
Sacramento
University of California Davis Comprehensive Cancer Center
Sacramento
MyMichigan Medical Center Saginaw
Saginaw
Oncology Hematology Associates of Saginaw Valley PC
Saginaw
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud
Dartmouth Cancer Center - North
Saint Johnsbury
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph
Heartland Regional Medical Center
Saint Joseph
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park
Regions Hospital
Saint Paul
United Hospital
Saint Paul
Sainte Genevieve County Memorial Hospital
Sainte Genevieve
Salinas Valley Memorial
Salinas
Huntsman Cancer Institute/University of Utah
Salt Lake City
LDS Hospital
Salt Lake City
Utah Cancer Specialists-Salt Lake City
Salt Lake City
Kaiser Permanente-San Diego Zion
San Diego
UC San Diego Medical Center - Hillcrest
San Diego
California Pacific Medical Center-Pacific Campus
San Francisco
Kaiser Permanente-San Francisco
San Francisco
Kaiser Permanente-Santa Teresa-San Jose
San Jose
Kaiser Permanente San Leandro
San Leandro
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo
Kaiser Permanente-San Marcos
San Marcos
Mills Health Center
San Mateo
Kaiser San Rafael-Gallinas
San Rafael
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint
Essentia Health Sandstone
Sandstone
North Coast Cancer Care
Sandusky
MaineHealth Cancer Care and IV Therapy - Sanford
Sanford
MaineHealth Cancer Care Center of York County
Sanford
Ridley-Tree Cancer Center
Santa Barbara
Kaiser Permanente Medical Center - Santa Clara
Santa Clara
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz
Santa Cruz Radiation Oncology Medical Group
Santa Cruz
Mission Hope Medical Oncology - Santa Maria
Santa Maria
Kaiser Permanente-Santa Rosa
Santa Rosa
Sutter Pacific Medical Foundation
Santa Rosa
Memorial Health University Medical Center
Savannah
MaineHealth Maine Medical Center- Scarborough
Scarborough
Community Medical Center
Scranton
FHCC at Northwest Hospital
Seattle
Fred Hutchinson Cancer Center
Seattle
Swedish Medical Center-First Hill
Seattle
University of Washington Medical Center - Montlake
Seattle
Virginia Mason Medical Center
Seattle
Grand View Hospital
Sellersville
Prisma Health Cancer Institute - Seneca
Seneca
UPMC Cancer Center at UPMC Northwest
Seneca
Sidney Kimmel Cancer Center Washington Township
Sewell
Saint Francis Regional Medical Center
Shakopee
ThedaCare Cancer Care - Shawano
Shawano
Sheboygan Physicians Group
Sheboygan
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan
Jewish Hospital Medical Center South
Shepherdsville
Memorial Hospital East
Shiloh
Saint Joseph Medical Center Hematology and Oncology - Silverdale
Silverdale
Siouxland Regional Cancer Center
Sioux City
Avera Cancer Institute
Sioux Falls
Sanford Cancer Center Oncology Clinic
Sioux Falls
Sanford USD Medical Center - Sioux Falls
Sioux Falls
Phelps Memorial Hospital Center
Sleepy Hollow
Robert Wood Johnson University Hospital Somerset
Somerville
VCU Community Memorial Health Center
South Hill
South Jordan Health Center
South Jordan
City of Hope South Pasadena
South Pasadena
MaineHealth Cancer Care and IV Therapy - South Portland
South Portland
Kaiser Permanente-South San Francisco
South San Francisco
Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth
Henry Ford Health Providence Southfield Hospital
Southfield
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven
Spartanburg Medical Center
Spartanburg
CoxHealth South Hospital
Springfield
Mercy Hospital Springfield
Springfield
Southern Illinois University School of Medicine
Springfield
Springfield Clinic
Springfield
Springfield Memorial Hospital
Springfield
Springfield Regional Cancer Center
Springfield
Springfield Regional Medical Center
Springfield
Mercy Hospital Saint Louis
St Louis
Mercy Hospital South
St Louis
Mercy Infusion Center - Chippewa
St Louis
Missouri Baptist Medical Center
St Louis
Siteman Cancer Center at Christian Hospital
St Louis
Siteman Cancer Center-South County
St Louis
Washington University School of Medicine
St Louis
Saint George Regional Medical Center
St. George
Saint Anthony's Hospital Cancer Care Center
St. Petersburg
Smilow Cancer Hospital Care Center at Long Ridge
Stamford
Staten Island University Hospital
Staten Island
Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights
Trinity's Tony Teramana Cancer Center
Steubenville
Aspirus Cancer Care - Stevens Point
Stevens Point
Marshfield Medical Center-River Region at Stevens Point
Stevens Point
Lakeview Hospital
Stillwater
Piedmont Henry Hospital
Stockbridge
Kaiser Permanente-Stockton
Stockton
Stony Brook University Medical Center
Stony Brook
Cleveland Clinic Cancer Center Strongsville
Strongsville
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay
Cancer Specialists of Tidewater-Suffolk
Suffolk
UT MD Anderson - Sugar Land
Sugar Land
Missouri Baptist Sullivan Hospital
Sullivan
Aurora Medical Center in Summit
Summit
Overlook Hospital
Summit
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale
Essentia Health Saint Mary's Hospital - Superior
Superior
ProMedica Flower Hospital
Sylvania
Franciscan Research Center-Northwest Medical Plaza
Tacoma
Moffitt Cancer Center
Tampa
Moffitt Cancer Center - McKinley Campus
Tampa
Moffitt Cancer Center-International Plaza
Tampa
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa
Tampa General Hospital
Tampa
MyMichigan Medical Center Tawas
Tawas City
Scott and White Memorial Hospital
Temple
Montefiore Medical Center-Einstein Campus
The Bronx
Sanford Thief River Falls Medical Center
Thief River Falls
Mercy Health - Saint Anne Hospital
Toledo
Mercy Health - Saint Vincent Hospital
Toledo
Mercy Health Sylvania Radiation Oncology Center
Toledo
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Toledo
Community Medical Center
Toms River
City of Hope South Bay
Torrance
Torrance Memorial Physician Network - Cancer Care
Torrance
Smilow Cancer Hospital-Torrington Care Center
Torrington
Munson Medical Center
Traverse City
Corewell Health Beaumont Troy Hospital
Troy
Dayton Physicians LLC - Troy
Troy
Upper Valley Medical Center
Troy
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee
Smilow Cancer Hospital Care Center-Trumbull
Trumbull
Legacy Meridian Park Hospital
Tualatin
Banner University Medical Center - Tucson
Tucson
University of Arizona Cancer Center-North Campus
Tucson
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers
SMC Center for Hematology Oncology Union
Union
UPMC Cancer Center-Uniontown
Uniontown
City of Hope Upland
Upland
Carle Cancer Center
Urbana
The Carle Foundation Hospital
Urbana
Kaiser Permanente Medical Center-Vacaville
Vacaville
Kaiser Permanente-Vallejo
Vallejo
Sutter Solano Medical Center/Cancer Center
Vallejo
Mount Sinai Doctors - Valley Stream
Valley Stream
Northwest Cancer Center - Valparaiso
Valparaiso
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver
Legacy Salmon Creek Hospital
Vancouver
Essentia Health Virginia Clinic
Virginia
Peninsula Cancer Institute-Cancer Specialists of Tidewater
Virginia Beach
Ridgeview Medical Center
Waconia
University Hospitals Sharon Health Center
Wadsworth
BASS Medical Group - Lennon
Walnut Creek
Epic Care Cyberknife Center
Walnut Creek
John Muir Medical Center-Walnut Creek
Walnut Creek
Kaiser Permanente-Walnut Creek
Walnut Creek
Mount Sinai - Wantagh
Wantagh
Advanced Breast Care Center PLLC
Warren
Henry Ford Health Warren Hospital
Warren
Henry Ford Madison Heights Hospital - Breast
Warren
Henry Ford Warren Hospital - GLCMS
Warren
Macomb Hematology Oncology PC
Warren
Saint Joseph Warren Hospital
Warren
South Pointe Hospital
Warrensville Heights
Northwestern Medicine Cancer Center Warrenville
Warrenville
Illinois CancerCare - Washington
Washington
Mercy Hospital Washington
Washington
UPMC Cancer Center-Washington
Washington
George Washington University Medical Center
Washington D.C.
Kaiser Permanente-Capitol Hill Medical Center
Washington D.C.
MedStar Georgetown University Hospital
Washington D.C.
MedStar Washington Hospital Center
Washington D.C.
Smilow Cancer Hospital-Waterbury Care Center
Waterbury
Smilow Cancer Hospital Care Center - Waterford
Waterford
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee
UW Cancer Center at ProHealth Care
Waukesha
ThedaCare Cancer Care - Waupaca
Waupaca
Aspirus Cancer Care-Wausau
Wausau
Marshfield Clinic-Wausau Center
Wausau
Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa
Wauwatosa
Aurora Cancer Care-Milwaukee West
Wauwatosa
Wilmot Cancer Institute at Webster
Webster
Moffitt Cancer Center at Wesley Chapel
Wesley Chapel
Aurora West Allis Medical Center
West Allis
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch
Chester County Hospital
West Chester
University of Cincinnati Cancer Center-West Chester
West Chester
Mercy Medical Center-West Lakes
West Des Moines
Reading Hospital
West Reading
Smilow Cancer Hospital Care Center - Westerly
Westerly
Saint Ann's Hospital
Westerville
UH Seidman Cancer Center at Saint John Medical Center
Westlake
William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster
Cleveland Clinic-Weston
Weston
Marshfield Medical Center - Weston
Weston
Wexford Health and Wellness Pavilion
Wexford
Wheeling Hospital/Schiffler Cancer Center
Wheeling
Ascension Via Christi Hospitals Wichita
Wichita
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre
Peninsula Cancer Institute-Williamsburg
Williamsburg
Divine Providence Hospital
Williamsport
Rice Memorial Hospital
Willmar
Asplundh Cancer Pavilion
Willow Grove
Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care
Winchester
Wake Forest University Health Sciences
Winston-Salem
Winter Haven Hospital
Winter Haven
AdventHealth Winter Park
Winter Park
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids
Kaiser Permanente-Caton Hill Medical Center
Woodbridge
Minnesota Oncology Hematology PA-Woodbury
Woodbury
Woodland Memorial Hospital
Woodland
Kaiser Permanente-Woodland Hills
Woodland Hills
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster
Sanford Cancer Center Worthington
Worthington
Fairview Lakes Medical Center
Wyoming
University of Michigan Health - West
Wyoming
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima
Avera Cancer Institute at Yankton
Yankton
Cancer Care Associates of York
York
UPMC Memorial
York
WellSpan Health-York Cancer Center
York
WellSpan Health-York Hospital
York
Rush-Copley Healthcare Center
Yorkville
Saint Elizabeth Youngstown Hospital
Youngstown
Huron Gastroenterology PC
Ypsilanti
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti
Genesis Healthcare System Cancer Care Center
Zanesville