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NCT07782164

Efficacy of Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study)

Traducción pendiente · disponible pronto
Reclutando

Descripción

The goal of this single-center observational cohort study, based on a registry combining retrospectively and prospectively collected data, is to investigate the short- and long-term effects of irreversible electroporation (IRE) in men and women over the age of 18 who receive IRE for recurrence of pelvic tumors not suitable for other local treatment options such as surgery, thermal ablation, and radiotherapy. The main question it aims to answer is whether IRE is safe in this population, and secondarily, whether it is effective in controlling local tumor recurrence.

Evidencia de la diana molecular en cáncer colorrectal

Aún no hay evidencia documentada en nuestra base para la diana o el fármaco de este ensayo. Esta sección crece a medida que se procesan nuevas publicaciones.

Criterios de Elegibilidad

Inclusion Criteria:

  • Measurable disease described on pre-treatment imaging (CT/MRI/PET-CT) (max 6 weeks prior);
  • IRE of a recurrent pelvic tumor;
  • Unsuitable for other local therapies (surgery/stereotactic body radiation therapy) as described during the multidisciplinary tumor board;

Exclusion Criteria:

  • If the treated tumor was biopsied directly prior to MWA and pathology proves the lesion to represent a benign entity;
  • Inadequate or insufficient data registered;
  • Inadequate or insufficient follow-up;

Información del Ensayo

NCT07782164
Reclutando
Sin fase definida
27 participantes
Abr 2025

Ubicaciones1

Netherlands (1)
Amsterdam UMC
Amsterdam